Buffalo Bills vs New England Patriots: Week 7 Betting Odds and Analysis
The Bills are heavy favorites heading into their AFC East clash against the Patriots, with the spread sitting at -7.5 at most sportsbooks. Buffalo’s high-powered offense, led by Josh Allen, is expected to dominate a New England defense that has struggled against mobile quarterbacks this season.
Key Betting Lines
Moneyline: Bills (-350), Patriots (+275) Over/Under: 48.5 points Spread: Bills -7.5
The Bills have covered in 4 of their last 5 home games, while the Patriots are just 2-6 against the spread in their last 8 road contests. For the latest updates and analysis on this matchup, check out the full bills vs patriots odds breakdown.
What to Watch
Buffalo’s offense ranks 3rd in the NFL in yards per game, while New England’s defense has allowed 25+ points in 3 of their last 4 games. Expect Josh Allen to target Stefon Diggs early and often.
New England’s rushing attack is the key. If Rhamondre Stevenson can control the clock, the Patriots could keep this close. However, Buffalo’s front seven has been stout against the run, allowing just 3.8 yards per carry.
Best Bet
Take the over 48.5 points. Both teams have shown offensive firepower, and Buffalo’s secondary is vulnerable to big plays. A 27-20 type game seems likely.

